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◎冯心怡

在实验室内,工程师正俯身在设备控制屏前,查看屏幕上跳动的数据;在仓库内,多台机器整装待发,即将被运送至国内外各类客户手中……这是记者近日走访上海原能细胞生物低温设备有限公司(下称“原能生物”)位于浦东新区惠南的研发基地看到的繁忙景象。

原能生物发源于原能细胞科技集团股份有限公司(下称“原能细胞”),也是上市公司开能健康投资细胞科技产业的重要组成部分。自2014年创立以来,原能细胞以“存原始细胞,储生命之能”为使命,深耕细胞生态圈,在2017年成功孵化原能生物,发展成为智能化细胞生物样本库行业的引领者。

“我们深耕细胞产业,不断进行研发投入,希望实现‘天下无穷人,地上无病人’的愿景。”原能细胞董事长庄乾坤在接受上海证券报专访时表示。

创新技术做低温存储领域的拓荒者

提及原能生物,创始人瞿建国是灵魂人物。他曾创立A股市场“老八股”之一的申华实业,后又创立开能健康,并带领其成为中国居家水处理行业的首家上市公司。2014年,他投身大健康产业,创立原能细胞,又在2017年创办原能生物,并亲任总工程师。

原能生物致力于先进细胞生物自动化低温存储装备的技术研发、产品设计与制造,以自动化、智能化的深低温生物样本存储设备为核心重点,直击前沿生物医药产业上下游的生物样本冻存痛点,提供创新解决方案。

“近几年,各行各业的机械化和自动化程度越来越高,但我们发现还有很多科学家要‘里三层外三层’地把自己裹严实了才能进入低温实验室,工作起来非常辛苦笨重。”庄乾坤说,“我们要做行业的引领者,不仅为客户提供单一的自动化存储设备,还能够实现设备与设备、库与库之间的联动,解放科学家们的双手,实现低温存储的无人值守。”

在原能生物的产品展厅,细胞复苏仪、程序降温仪、自动化存储设备等各类科技感满满的产品陈列其中,令人目不暇接。

一支约一拃长、一指宽的真空套管,看似平平无奇,实则暗藏乾坤——在脱离外部保温设备时,它就像一个小型保温杯,能够保障套管内部维持零下196摄氏度的低温,保温时长约1小时。此外,套管外部设有RFID(无线射频识别)、数字码和条形码,能够有效防止样本的混淆与错用。

做低温存储并不是一件易事。“我们的研发人员不仅要懂机械、人工智能,还要懂细胞生物学、深低温冷冻学,这些知识和技术环环相扣。产品看起来很简单,但要形成系统的解决方案,还是需要有高技术含量。”庄乾坤表示。

截至2024年12月,原能生物累计申请国内外专利600余项,获得500余个授权,还拥有超70个软件著作权。

布局产业做构建细胞生态圈的“织网人”

开能健康主要生产制造水处理产品,致力于改善人居水环境品质。作为开能健康旗下企业,原能生物却选择了细胞产业这条道路。

为什么不延续拓展开能健康业已成熟的主营业务,反而切入新赛道?

庄乾坤给出了解答:“其实开能健康和原能生物的产业与大健康息息相关,我们所服务的客群也都是一群追求健康生活、品质生活的客户。”她认为,净水设备能够从最基础的层面保障人类健康,而细胞产业则是从另一个维度维护身体健康。

“细胞健康了,人就健康了;细胞有活力,人就年轻了;细胞自在了,人就长寿了。”走进原能生物的研发中心,墙上一条醒目的标语映入眼帘,这是瞿建国对细胞科技的看法。

研发细胞深低温存储设备是瞿建国在细胞产业迈出的最为重要的一步,但他的愿景远不止于此。除原能生物外,原能细胞旗下还有原天生物、基元美业、莱森原等生态圈企业,涵盖细胞存储、自动化生物样本存储装备、免疫治疗药物等多个领域。据介绍,原能细胞以打造标准化、智能化、产业化细胞库网络为核心业务,在上海张江打造了首个无人值守的5G全自动细胞库。

“我们的产品应用场景广泛,公司客户包括三甲医院、疾控中心、生物药厂、动物实验中心、植物所等,一些产品已经销往美国、日本等国家。”庄乾坤说,不同客户对细胞存储设备的温度要求不同,存储的细胞来源也各不相同,这就要求公司产品能够实现个性化和定制化。

在原能生物的24小时客户运维中心,一整面墙的电子显示屏实时展示着海内外设备的运行状况。“一旦设备出现问题或者警报,我们都能第一时间通知客户,并且远程协助他们解决。”庄乾坤说。

展望未来做永不停歇的奔跑者

“上医治未病”,原能细胞秉持着这样的理念,加码布局大健康行业。

在庄乾坤看来,大健康意味着主动健康,原能细胞要做的就是像储蓄财富一样储蓄健康。“如果人们在年轻时有机会把自己的细胞存储起来,在未来生病时,他们就能使用细胞疗法进行治疗、抗衰,为生活带来不同的可能性。”她相信,随着科技的持续发展,未来的某一天,细胞疗法的价格将大幅下降,变成每一个普通人都能负担的治疗方法。

与常见的普通液氮罐等低温存储设备相比,原能生物的自动化设备价格较高,如何降低成本、提升生产效率,是原能生物未来需要解决的问题。原能生物正努力扩大市场、布局销售,“未来几年,希望我们的设备销售收入可以实现每年翻一番的增长。”庄乾坤说,在政策支持下,原能生物将逐步走向产业化阶段,此前的高额研发投入或将迎来收获期。

2022年,原能生物完成4.1亿元A轮融资,今年将启动B轮融资,公司希望可以早日登陆科创板。“未来我们要与时俱进,不断升级技术,打造出Pro版、Plus版新产品。”庄乾坤说,“我相信第三方的细胞存储业务将有无限的可能和发展,细胞产业大有可为。”

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