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  上海4月25日电(记者陈静)今年,中国百白破疫苗接种方案迎来重大调整:在全国范围内实施将此前3月龄、4月龄、5月龄、18月龄各接种1剂次百白破疫苗和6周岁接种1剂次吸附白喉-破伤风联合疫苗的免疫程序,调整为2月龄、4月龄、6月龄、18月龄、6周岁各接种1剂次百白破疫苗的免疫程序。

  对此,上海交通大学医学院附属上海儿童医学中心新生儿科主任医师步军25日接受采访时指出,近年来,因为多种因素,成人体或者母体体内的抗体水平降低,导致包括婴儿在内的易感人群增加;与此同时,检测手段丰富了,化验的敏感度高了,查出来确诊的病例就越来越多了。4月25日是第39个“全国儿童预防接种日”,今年的宣传主题为“打疫苗防疾病保健康”,旨在号召全社会共同行动,以疫苗为“盾”,守护儿童健康成长,筑牢全民免疫防线。

  上海市徐汇区疾病控制预防中心(上海市徐汇区卫生健康监督所)免疫规划科副主任医师吴强松介绍,不论是接种疫苗还是自然感染所获得的保护性抗体均不能获得终生保护,通常疫苗接种3至5年后保护性抗体水平下降,12年后抗体几乎消失。在2024年,我们观察到百日咳聚集性疫情在中小学校等场所频繁发生。本次将6周岁白破疫苗调整为百白破疫苗正是考虑到上述状况,希望尽量减少学龄儿童的感染。

  “疫苗的程序从3月龄提前到了2月龄,就是为了让小月龄的婴幼儿更早地获得百日咳的免疫力。”吴强松直言。现在随着二胎、多胎家庭增加,家中大宝将百日咳传给小宝的现象频繁发生。对于小月龄的婴儿,如果没有接种疫苗的话,身体中的保护性抗体来自于母传抗体,出生后母传抗体还会快速衰减。此外,有研究表明,即使产妇自身针对百日咳的保护性抗体也是不足的。

  按照世界卫生组织(WHO)的数据,通过接种疫苗,每年可以避免200万到300万人的死亡。疫苗可预防传染病,通过接种脊髓灰质炎疫苗,中国从1995年之后已实现阻断脊髓灰质炎病毒的传播,成千上万儿童免于残疾的结局。推广乙肝疫苗接种以后,中国5岁儿童乙肝疫苗的病毒携带率大幅下降。

  吴强松介绍,除了儿童接种的疫苗,目前成人可接种的疫苗也很多,比如:流感疫苗、肺炎疫苗、宫颈癌疫苗以及带状疱疹疫苗等等。

  关于“疫苗犹豫”,吴强松表示,“疫苗犹豫”确实存在。比如流感疫苗和肺炎疫苗等非免疫规划疫苗,在疫苗可及的情况下,受种者不愿意接种疫苗。一些老年人不愿意接种流感疫苗或肺炎疫苗,主要在于对安全性和有效性的信心不足。“事实上,疫苗整体安全性很高。监测数据显示,接种流感疫苗和肺炎疫苗后发生严重异常反应的风险是非常非常低的。”吴强松说。

  此外,针对呼吸道合胞病毒(RSV)这一婴儿重症感染高发的病毒,创新预防手段——长效单克隆抗体已经在中国获批使用。北京市、天津市、上海市、湖北省等地率先探索创新管理模式,将RSV预防纳入更便捷的服务场景中,为婴儿出生起即构建免疫屏障。

  单抗与疫苗有怎样的区别?步军表示,疫苗是主动免疫,通过激活人体内免疫系统产生抗体。单抗是直接给身体抗体。目前,很多家长对单抗认识不足,以为就是疫苗。有人认为,孩子太小,打针多了怕副作用;有人怀疑是否需要多打一针。这位专家指出,RSV广泛存在,传染性很强,年龄越小的孩子感染后症状就越重:喘息、需要吸氧甚至需要辅助呼吸设备支持。尤其对一些早产儿、低体重儿或者有先心病等先天性疾病患儿,感染RSV风险更大。

  “感染合胞病毒对孩子肺功能影响很大。”步军说,小婴儿呼吸道的黏膜屏障没有发育健全,黏膜受损后就增加了敏感性,以后哮喘的发生率明显升高;有些早产儿合并有支气管肺发育不良,感染RSV后病程会明显延长。

  吴强松指出,防范呼吸道传染病,非药物干预措施对于小宝宝来说很难做到,接种疫苗显得尤为重要。为减少家庭内传播,大人回家后记得先洗手、脱掉外衣再和孩子互动,家中最好每天开窗通风两到三次,每次半个小时,家中如有人生病了要做好消毒,一些不适合消毒的孩子玩具、绘本,可以在阳光下暴晒。

  这位专家也建议家长接种流感疫苗,避免感染并传染家中孩子。(完)

  中新社天津4月25日电题:从批卷到育心AI助力“未来课堂”加速成型

  中新社记者王君妍周亚强

  “老师不用再一张张批卷了,包括作文等主观题的批改,系统几分钟就能完成,而且还能自动分析错题类型。”在中国教育装备展示会现场,参观者体验AI智能批阅系统的使用过程:扫描上传试卷、系统识别答题、同步生成反馈报告,整个流程高效便捷。

  第85届中国教育装备展示会25日在天津开幕。展会以“人工智能引领教育装备高质量发展”为主题,展示教育装备产业最新成果、创新应用和发展趋势。

  现场,1200余家参展企业集中亮相。记者在展区看到,AI技术正逐步融入教育教学多个场景。批改试卷、协助备课、心理疏导、体育测试……“未来课堂”加速变为现实。

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